OncoMatch/Clinical Trials/NCT02297217
Chemoradiotherapy for Advanced Esophageal Cancer
Is NCT02297217 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies Carboplatin and Taxol (paclitaxel) for esophageal cancer.
Treatment: Carboplatin and Taxol (paclitaxel) — This study aims to show that the addition of carboplatin and paclitaxel chemotherapy to a palliative course of external beam radiation treatment improves both dysphagia relief and patient quality of life in patients with unresectable esophageal cancer.
Check if I qualifyExtracted eligibility criteria
Treatments studied
Chemotherapy
Cancer type
Esophageal Carcinoma
Performance status
ECOG 0–2(Ambulatory, capable of self-care)
Prior therapy
Cannot have received: radiation therapy
Previous radiotherapy delivered to the chest.
Cannot have received: cytotoxic chemotherapy
Previous chemotherapy for esophageal cancer
Lab requirements
Blood counts
Hemoglobin > 100g/L; Platelet count > 100x10E9/L; Absolute neutrophil count > 1.5x10E9/L
Kidney function
Calculated creatinine clearance ≥ 50 mL/min using the Cockcroft-Gault formula
Liver function
AST and ALT ≤ 2.5x ULN (≤ 5 if liver metastases); total bilirubin ≤ 1.5x ULN
Hematological function as defined by the following laboratory parameters: Hemoglobin > 100g/L; Platelet count > 100x10E9/L; Absolute neutrophil count > 1.5x10E9/L. Renal function to undergo chemotherapy as defined by the following laboratory parameters: AST and ALT ≤ 2.5x ULN (≤ 5 if liver metastases); total bilirubin ≤ 1.5x ULN; Calculated creatinine clearance ≥ 50 mL/min using the Cockcroft-Gault formula
Structured fields extracted by AI. May contain errors — verify against the official protocol.
Frequently asked questions
Is NCT02297217 currently recruiting?
Yes, this trial is currently recruiting patients.
Can patients have received prior systemic therapy?
No. This trial requires treatment-naive patients — prior systemic therapy is an exclusion criterion.
Could you qualify for this trial?
Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.
Check if I qualifyRelated pages