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OncoMatch/Clinical Trials/NCT02215889

Partial Liver Segment 2/3 Transplantation Study

Is NCT02215889 recruiting? Yes, currently enrolling (May 2026). This Phase 1/2 trial studies non-drug interventions for colorectal cancer.

Phase 1/2RecruitingOslo University HospitalNCT02215889Data as of May 2026

The patients will receive hepatectomy as a 2 stage procedure. In the first surgical procedure liver segments 2-3 are removed and liver donor segments 2-3 inserted. After growth of donor segments 2-3, the remaining liver segments of the recipient are removed. The patient will at this time have only donor liver tissue in place.

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Extracted eligibility criteria

Cancer type

Colorectal Cancer

Disease stage

Metastatic disease required

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

Must have received: chemotherapy

All patients should have received at least 8 weeks of chemotherapy.

Cannot have received: palliative resection of primary CRC tumor

Palliative resection of primary CRC tumor.

Lab requirements

Blood counts

Hb >10g/dl, neutrophiles >1.0 (after any G-CSF), TRC >75

Kidney function

Creatinine <1.25 x upper normal level

Liver function

Bilirubin <2 x upper normal level, ASAT, ALAT <5 x upper normal level, Albumin above lower normal level

Satisfactory blood tests: Hb >10g/dl, neutrophiles >1.0 (after any G-CSF), TRC >75, Bilirubin<2 x upper normal level, ASAT,ALAT<5 x upper normal level, Creatinine <1.25 x upper normal level. Albumin above lower normal level.

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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