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OncoMatch/Clinical Trials/NCT01891318

Neoadjuvant Radiosurgery for Resectable Brain Metastases: Phase I/II Study

Is NCT01891318 recruiting? Yes, currently enrolling (May 2026). This Phase 1/2 trial studies non-drug interventions for tumors metastatic to brain.

Phase 1/2RecruitingCase Comprehensive Cancer CenterNCT01891318Data as of May 2026

This Phase I/II trial studies the ability to stop brain metastases from coming back after treatment with radiosurgery followed by surgical resection. It will also evaluate the side effects of these combined treatments and help determine the best radiosurgery dose. Radiosurgery focuses the x-rays directly to the tumor and cause less damage to the normal tissue in the brain.

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Extracted eligibility criteria

Disease stage

Metastatic disease required

Prior therapy

Cannot have received: whole brain radiotherapy

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • University Hospitals Cleveland Medical Center, Case Comprehensive Cancer Center · Cleveland, Ohio
  • Cleveland Clinic, Case Comprehensive Cancer Center · Cleveland, Ohio

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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