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OncoMatch/Clinical Trials/NCT00107289

Iodine I 131 Metaiodobenzylguanidine in Treating Patients With Recurrent, Progressive, or Refractory Neuroblastoma or Malignant Pheochromocytoma or Paraganglioma

Is NCT00107289 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies iobenguane I 131 for neuroblastoma.

Phase 2RecruitingMemorial Sloan Kettering Cancer CenterNCT00107289Data as of May 2026

Treatment: iobenguane I 131The purpose of this research study is to find how active and safe 131 I-MIBG is in patients with resistant neuroblastoma, malignant pheochromocytoma and malignant paraganglioma.

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Extracted eligibility criteria

Cancer type

Neuroblastoma

Disease stage

Required: Stage PROGRESSIVE, REFRACTORY

history of tumor progression or recurrence or failure to achieve complete response with standard therapy; evaluable disease on MIBG scan

Lab requirements

Kidney function

grade 2 or less renal toxicity

Liver function

grade 2 or less hepatic toxicity

Cardiac function

grade 2 or less cardiac toxicity

renal, cardiac, hepatic, pulmonary, gastrointestinal and neurologic toxicity should all be grade 2 or less. A grade 3 hearing deficit is acceptable.

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Memorial Sloan Kettering Cancer Center · New York, New York

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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