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OncoMatch/Clinical Trials/NCT00107289

Iodine I 131 Metaiodobenzylguanidine in Treating Patients With Recurrent, Progressive, or Refractory Neuroblastoma or Malignant Pheochromocytoma or Paraganglioma

Is NCT00107289 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies iobenguane I 131 for neuroblastoma.

Phase 2RecruitingMemorial Sloan Kettering Cancer CenterNCT00107289Data as of Jun 2026

Treatment: iobenguane I 131The purpose of this research study is to find how active and safe 131 I-MIBG is in patients with resistant neuroblastoma, malignant pheochromocytoma and malignant paraganglioma.

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Extracted eligibility criteria

Treatments studied

Other

iobenguane I 131

Cancer type

Neuroblastoma

Disease stage

Required: Stage PROGRESSIVE, REFRACTORY

history of tumor progression or recurrence or failure to achieve complete response with standard therapy; evaluable disease on MIBG scan

Demographics

Ages 1–21

Lab requirements

Kidney function

grade 2 or less renal toxicity

Liver function

grade 2 or less hepatic toxicity

Cardiac function

grade 2 or less cardiac toxicity

renal, cardiac, hepatic, pulmonary, gastrointestinal and neurologic toxicity should all be grade 2 or less. A grade 3 hearing deficit is acceptable.

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Memorial Sloan Kettering Cancer Center · New York, New York

Showing up to 5 US sites.

See all sites on ClinicalTrials.gov →

Frequently asked questions

Is NCT00107289 currently recruiting?

Yes, this trial is currently recruiting patients.

What disease stage is eligible?

Stage PROGRESSIVE or REFRACTORY is required.

Is there an age limit?

Yes. Patients must be 21 years or younger and at least 1 years old.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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